HRID441887

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10868

Dicyclohexylcarbodiimide

C13H22N2

HCID14855682

4-(Pyrrolidin-1-yl)butanoic acid--hydrogen chloride (1/1)

C8H16ClNO2

结构：CCCC1(CCC)Oc2cc(CC3CC3)cc(O)c2C2=C1CCN(CC=Cc1ccccc1)C2

HCID54479289

未命名化合物

PRODUCTS

生成物

结构：CCCC1(CCC)Oc2cc(CC3CC3)cc(OC(=O)CCCN3CCCC3)c2C2=C1CCN(CC=Cc1ccccc1)C2.Cl

HCID68118892

未命名化合物

PROCEDURE

实验过程

2-Cinnamyl-8-cyclopropylmethyl-5,5-di(1-propyl)-10-hydroxy-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-d]pyridine, γ-pyrrolidinobutyric acid hydrochloride and dicyclohexyl-carbodiimide are reacted in equimolar amounts according to Example 1 to form the desired product.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-7678024ad67046cd9c9f3b15458cba1f
来源数据集: uspto-grants-1977_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04042694
来源说明: uspto-grants-1977_08

反应 SMILES

[CH2:1]([N:10]1[CH2:15][C:14]2[C:16]3[C:29]([OH:30])=[CH:28][C:27]([CH2:31][CH:32]4[CH2:34][CH2:33]4)=[CH:26][C:17]=3[O:18][C:19]([CH2:23][CH2:24][CH3:25])([CH2:20][CH2:21][CH3:22])[C:13]=2[CH2:12][CH2:11]1)[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[ClH:35].[N:36]1([CH2:41][CH2:42][CH2:43][C:44](O)=[O:45])[CH2:40][CH2:39][CH2:38][CH2:37]1.C1(N=C=NC2CCCCC2)CCCCC1>>[ClH:35].[CH2:1]([N:10]1[CH2:15][C:14]2[C:16]3[C:29]([O:30][C:44](=[O:45])[CH2:43][CH2:42][CH2:41][N:36]4[CH2:40][CH2:39][CH2:38][CH2:37]4)=[CH:28][C:27]([CH2:31][CH:32]4[CH2:34][CH2:33]4)=[CH:26][C:17]=3[O:18][C:19]([CH2:20][CH2:21][CH3:22])([CH2:23][CH2:24][CH3:25])[C:13]=2[CH2:12][CH2:11]1)[CH:2]=[CH:3][C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1