Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 441930Generated: October 30, 2026

Phosphorus pentachloride → 8-Quinolinesulfonyl chloride

https://huagongshe.com/reaction/441930

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus pentachlorideHCID 24819—
Reactant8-Quinolinesulfonic acidHCID 66561—
Product8-Quinolinesulfonyl chlorideHCID 29220—

Reaction Conditions

Temperature140 °C

Reaction Steps

Equal quantities by weight of 8-quinolinesulfonic acid and phosphorous pentachloride were ground together in a mortar. This mixture was then refluxed at approximately 140° C. for 3 hours after which work-up of the reaction mixture gave 8-quinolinesulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04043922
Source datasetuspto-grants-1977_08
ORD IDord-987237a46b904b57ac722dd7691348d5
Source noteuspto-grants-1977_08