Hydrochloric Acid → 5-(3,5-Dicarboxy-phenylazo)-2-hydroxy-phenylacetic acid

HRID 4420Notes

Reaction equation

HRID 4420 reaction equation
C[O:2][C:3]([C:5]1[CH:6]=[C:7]([N:15]=[N:16][C:17]2[CH:18]=[CH:19][C:20]([OH:27])=[C:21]([CH2:23][C:24]([OH:26])=[O:25])[CH:22]=2)[CH:8]=[C:9]([C:11]([O:13]C)=[O:12])[CH:10]=1)=[O:4].[OH-].[Na+].C(O)C.Cl>O>[C:11]([C:9]1[CH:8]=[C:7]([N:15]=[N:16][C:17]2[CH:18]=[CH:19][C:20]([OH:27])=[C:21]([CH2:23][C:24]([OH:26])=[O:25])[CH:22]=2)[CH:6]=[C:5]([C:3]([OH:4])=[O:2])[CH:10]=1)([OH:13])=[O:12]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 14798Sodium HydroxideHCID 1273242-Hydroxy-5-((3,5-bis(methoxycarbonyl)phenyl)azo)benzeneacetic acid

Product 1

HCID 1357361795-(3,5-Dicarboxy-phenylazo)-2-hydroxy-phenylacetic acid

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

12 g of 5-(3,5-bis-(methoxycarbonyl)-phenylazo)-2-hydroxyphenylacetic acid, 350 ml of water and 7 g of sodium hydroxide were boiled for 1 hour. 50 ml of ethanol was added, and the solution was diluted with water to 500 ml. The hot solution was acidified with hydrochloric acid to pH 2 and cooled. The crystals were filtered off, washed with water and dried.

Workup

  1. temperaturecooled
  2. filtrationThe crystals were filtered off
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-5c78bd6caf8a486a9043ac61fe6070d4
Source dataset
uspto-grants-1988_02
Patent number
US04725676

Reaction notes

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