HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → HCID 21416538, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2-Amino-3-hydroxyoctanoic acid | HCID 18790801 | — |
| Reactant | Diisobutylaluminumhydride | HCID 21225700 | — |
| Reactant | HCID 21416541 | HCID 21416541 | — |
| Reactant | HCID 53991059 | HCID 53991059 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 21416538 | HCID 21416538 | — |
Reaction Steps
Protect the amino function in the 2-amino-3-hydroxy-octanoic acid by conversion thereof to an acetamido function by reaction with acetic anhydride, then esterify the resultant 2-acetamido-3-hydroxyoctanoic acid with methanol; reduce the resultant 2-acetamido-3-hydroxyoctanoic acid methyl ester with di-isobutylaluminum hydride according to known procedures to obtain 2-acetamido-3-hydroxyoctanal.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04044123 |
| Source dataset | uspto-grants-1977_08 |
| ORD ID | ord-1a7b7a89240346628843ee1eecaeb263 |
| Source note | uspto-grants-1977_08 |