HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Fluoro-2-methoxy-4-nitrobenzene → 4-Fluoro-3-methoxyaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Fluoro-2-methoxy-4-nitrobenzene | HCID 14451968 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 4-Fluoro-3-methoxyaniline | HCID 2774533 | — |
Reaction Steps
A suspension of 10 grams of 2-fluoro-5-nitroanisole and 100 ml. of dioxane is reduced catalytically under 40 p.s.i. of hydrogen and 1.0 gram of 5% Pd/C. After the uptake of hydrogen ceases, the catalyst is filtered, and the filtrate is concentrated in vacuo to yield 4-fluoro-3-methoxyaniline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04044049 |
| Source dataset | uspto-grants-1977_08 |
| ORD ID | ord-9ac8f6ce11bc48d6b36b1c2544316579 |
| Source note | uspto-grants-1977_08 |