Potassium Hydroxide → HCID 54002285, compound

Participants

Reaction Steps

A mixture of 2 g. of 3-allyl-5-(4'-fluorophenyl)2-hydroxy-benzoic acid, 5 g. of potassium hydroxide pellets and 2 ml. of water was heated under nitrogen in an oil bath at 170° C. for 1 hour with occasional stirring. The reaction mixture was cooled, dissolved in water, and the solution acidified. The product was extracted into ether. After drying the ether solution, and removing the ether, the product was recrystallized from benzene to yield 1.37 g., m.p. 196° -200° C. One more recrystallization from benzene raised the m.p. to 198° -201° C.

Provenance & Evidence