Hydrogen Peroxide → HCID 22756225, compound

HRID 442320Notes

Reaction equation

HRID 442320 reaction equation
[OH:1][OH:2].[OH-:3].[Na+].[C:5]1([CH3:19])[CH:10]=[CH:9][C:8]([O:11][C:12]([CH2:14][CH2:15][C:16](Cl)=[O:17])=[O:13])=[CH:7][CH:6]=1.O=O>CCOCC>[C:5]1([CH3:19])[CH:10]=[CH:9][C:8]([O:11][C:12]([CH2:14][CH2:15][C:16]([O:1][O:2][C:16](=[O:17])[CH2:15][CH2:14][C:12]([O:11][C:8]2[CH:7]=[CH:6][C:5]([CH3:19])=[CH:10][CH:9]=2)=[O:3])=[O:17])=[O:13])=[CH:7][CH:6]=1

Participants

6

Reactant 4

HCID 784Hydrogen PeroxideHCID 977OxygenHCID 14798Sodium HydroxideHCID 227562303-(p-Tolyloxycarbonyl)propionyl chloride

Product 1

HCID 22756225HCID 22756225, compoundYield 83.9%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To a vigorously stirred solution of 2.0 g. (0.029 mole) of 50% H2O2 and 25.2 g. (0.063 mole) of aqueous 10% sodium hydroxide at 10°-14° C. was added slowly 10.9 g. (0.0483 mole) of 3-(p-tolyloxycarbonyl)propionyl chloride in ether solution. The resulting reaction mixture was stirred for an additional three hours. After a work-up similar to that in Example I 9.1 g. (theory, 10.0 g.) of white solid, m.p. 94°-106° C. (decomp.) was obtained. The assay according to "active oxygen" content was 92.3% and the corrected yield was 83.9%.

Workup

  1. customThe resulting reaction mixture
  2. custom(theory, 10.0 g.) of white solid, m.p. 94°-106° C. (decomp.) was obtained

Sources & evidence

ORD record
ord-93f24590d2db41a19529dfc130add50e
Source dataset
uspto-grants-1977_08
Patent number
US04045427

Reaction notes

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