Oxalic Acid → HCID 21415171, compound

HRID 442512Notes

Reaction equation

HRID 442512 reaction equation
[C:1]([OH:6])(=[O:5])[C:2]([OH:4])=[O:3].[CH2:7]([S:14][CH:15]([C:24]1[CH:29]=[CH:28][C:27]([Cl:30])=[CH:26][CH:25]=1)[CH2:16][CH2:17][CH2:18][N:19]1[CH:23]=[CH:22][N:21]=[CH:20]1)[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13]>CCOCC>[C:1]([OH:6])(=[O:5])[C:2]([OH:4])=[O:3].[CH2:7]([S:14][CH:15]([C:24]1[CH:29]=[CH:28][C:27]([Cl:30])=[CH:26][CH:25]=1)[CH2:16][CH2:17][CH2:18][N:19]1[CH:23]=[CH:22][N:21]=[CH:20]1)[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13]

Participants

4

Reactant 2

HCID 971Oxalic AcidHCID 21415172HCID 21415172, compound

Product 1

HCID 21415171HCID 21415171, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Oxalic acid in ether was added dropwise to a stirred solution of 2.0 g. of 1-[4-heptylthio-4-(4-chlorophenyl) butyl]imidazole in 30 ml. of anhydrous ether until precipitation was complete. The product was filtered off, washed with ether, air dried, and recrystallized from to yield 1-[4-heptylthio-4-(4-chlorophenyl)butyl]imidazole oxalate, m.p. 93-94.5° C.

Workup

  1. customof anhydrous ether until precipitation
  2. filtrationThe product was filtered off
  3. washwashed with ether, air
  4. customdried
  5. customrecrystallized from

Sources & evidence

ORD record
ord-cd5157f163f44a04bbce985ab6bff22a
Source dataset
uspto-grants-1977_08
Patent number
US04045568

Reaction notes

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