HCID 21415018, compound → HCID 21415028, compound

HRID 442530Notes

Reaction equation

HRID 442530 reaction equation
C([N:8]1[CH2:13][CH2:12][O:11][CH:10]([CH2:14][C:15]23[CH2:29][CH:22]([C:23]4[CH:24]=[CH:25][CH:26]=[CH:27][C:28]=42)[C:21]2[C:16]3=[CH:17][CH:18]=[CH:19][CH:20]=2)[CH2:9]1)C1C=CC=CC=1.[C:30](=[O:36])([O-])[O:31][CH2:32][CH2:33]Cl>C1(C)C=CC=CC=1>[CH2:32]([O:31][C:30]([N:8]1[CH2:13][CH2:12][O:11][CH:10]([CH2:14][C:15]23[CH2:29][CH:22]([C:23]4[CH:24]=[CH:25][CH:26]=[CH:27][C:28]=42)[C:21]2[C:16]3=[CH:17][CH:18]=[CH:19][CH:20]=2)[CH2:9]1)=[O:36])[CH3:33]

Participants

4

Reactant 2

HCID 21415018HCID 21415018, compoundHCID 22631361Chloroethyl carbonate

Product 1

HCID 21415028HCID 21415028, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A solution of 9-(4-benzyl-2-morpholinylmethyl)-9,10-dihydro-9,10-methanoanthracene (590 mg) and chloroethyl carbonate (671 mg) in dry toluene was refluxed for 3 hours. The reaction solution was washed with water, dried over anhydrous sodium sulfate and evaporated to dryness to give 9-(4-ethoxycarbonyl-2-morpholinylmethyl)-9,10-dihydro-9,10-methanoanthracene, M.P. 143° - 144.5° C.

Workup

  1. washThe reaction solution was washed with water
  2. dry with materialdried over anhydrous sodium sulfate
  3. customevaporated to dryness

Sources & evidence

ORD record
ord-6a78a2a7f108428992509e75dfaca392
Source dataset
uspto-grants-1977_08
Patent number
US04045560

Reaction notes

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