HCID 54203958, compound → HCID 53758858, compound

Participants

Reaction Steps

Compound 22b was prepared from 5-bromo4-chloro-7-[(1,3-dihydroxypropoxy)methyl]pyrrolo[2,3-d]pyrimidine by the method described for 22a to yield 0.27 g (20%). mp=170°-172° C. 1H NMR (DMSO-d6): δ3.15-3.50 (m, 5); 4.59 (t, 2, exchanges with D2O, OH); 5.57 (s, 2, C-1'), 6.80 (bs, 2, exchanges with D2O, NH2); 7.53 (s, 1, C-6); 8.11 (s, 1, C-2). Anal. Calcd. for C10H13N4O3Br. (C,H,N).

Provenance & Evidence