HCID 54310262, compound → HCID 54057494, compound

Participants

Reaction Steps

Compound 22c was prepared from 4-chloro-5-iodo-7-[(1,3-dihydroxypropoxy)methyl]pyrrolo[2,3-d]pyrimidine by the method described for 22a to yield 0.20 g (51%). mp=177°-177.5° C. 1H NMR (DMSO-d6): δ3.22-3.52 (m, 5); 4.58 (t, 2, exchanges with D2O, OH); 5.57 (s, 2, C-1'); 6.66 (bs, 2, exchanges with D2O, NH2); 7.55 (s, 1, C-6); 8.11 (s, 1, C-2). Anal. for C10H13N4O3I. (C,H,N).

Provenance & Evidence