Tin tetrachloride → HCID 406957, compound

HRID 442660Notes

Reaction equation

HRID 442660 reaction equation
[CH2:1]1[O:9][C:8]2[CH:7]=[CH:6][C:5]([CH2:10][C:11]([O:13][CH3:14])=[O:12])=[CH:4][C:3]=2[O:2]1.Cl[Sn](Cl)(Cl)Cl.[F:20][C:21]1[CH:29]=[CH:28][C:24]([C:25](Cl)=[O:26])=[CH:23][CH:22]=1>C(Cl)Cl>[F:20][C:21]1[CH:29]=[CH:28][C:24]([C:25]([C:6]2[CH:7]=[C:8]3[O:9][CH2:1][O:2][C:3]3=[CH:4][C:5]=2[CH2:10][C:11]([O:13][CH3:14])=[O:12])=[O:26])=[CH:23][CH:22]=1

Participants

5

Reactant 3

HCID 24287Tin tetrachlorideHCID 678794-Fluorobenzoyl chlorideHCID 266588Methyl 2-(1,3-dioxaindan-5-yl)acetate

Product 1

HCID 406957HCID 406957, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title compound was prepared from methyl 3,4-methylenedioxyphenylacetate (340 mg, 1.75 mmol) in CH2Cl2 (8 mL), SnCl4 (1.0M solution in CH2Cl2 ; 3.5 mL, 3.5 mmol) and 4-fluorobenzoyl chloride (270 μL, 2.28 mmol) as a solid (350 mg, 63%). 1H NMR (CDCl3) 7.81 (m, 2H), 7.13 (m, 2H), 6.85 (s, 1H), 6.84 (s, 1H), 6.04 (s, 2H), 3.79 (s, 2H), 3.61 (s, 3H).

Sources & evidence

ORD record
ord-a591c70d27c64f7698c35e5f1d4c5e65
Source dataset
uspto-grants-1999_04
Patent number
US05891871

Reaction notes

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