Phosphorus oxide (P4O10) → HCID 53721998, compound

HRID 442681Notes

Reaction equation

HRID 442681 reaction equation
[CH2:1]1[O:9][C:8]2[CH:7]=[CH:6][C:5]([CH2:10][C:11]([O:13][CH3:14])=[O:12])=[CH:4][C:3]=2[O:2]1.[CH3:15][O:16][C:17]1[CH:18]=[C:19]([CH:23]=[CH:24][C:25]=1[N+:26]([O-:28])=[O:27])[C:20](O)=[O:21].O=P12OP3(OP(OP(O3)(O1)=O)(=O)O2)=O>C(Cl)CCl>[CH2:1]1[O:2][C:3]2[C:8](=[CH:7][C:6]([C:20](=[O:21])[C:19]3[CH:23]=[CH:24][C:25]([N+:26]([O-:28])=[O:27])=[C:17]([O:16][CH3:15])[CH:18]=3)=[C:5]([CH2:10][C:11]([O:13][CH3:14])=[O:12])[CH:4]=2)[O:9]1

Participants

5

Reactant 3

HCID 14812Phosphorus oxide (P4O10)HCID 787643-Methoxy-4-nitrobenzoic acidHCID 266588Methyl 2-(1,3-dioxaindan-5-yl)acetate

Product 1

HCID 53721998HCID 53721998, compound

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent

Procedure

The title compound was prepared from methyl 3,4-methylenedioxyphenylacetate (1.6 g, 8.0 mmol) in ClCH2CH2Cl (50 mL), 3-methoxy-4-nitrobenzoic acid (1.8 g, 9.3 mmol) and P2O5 (4 g) as a light yellow solid (1.2 g, 3.2 mmol, 40%). 1H NMR (CDCl3) 7.84 (d, J=8.2, 1H), 7.54 (d, J=1.4, 1H), 7.32 (dd, J=8.2, 1.4, 1H), 6.85 (s, 2H), 6.07 (s, 2H), 4.00 (s, 3H), 3.85 (s, 2H), 3.64 (s, 3H).

Sources & evidence

ORD record
ord-75313cb549194e36ac6e509f53a13fad
Source dataset
uspto-grants-1999_04
Patent number
US05891871

Reaction notes

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