Hydrochloric Acid → HCID 178510735, compound

Participants

Reaction Steps

5-(9H-xanthen-9-ylmethyl)-5-[4-(1H-tetrazol-5-yl)phenyl]hydantoin (3.2 g, 7.6 mmol) was heated with aqueous sodium hydroxide (2M, 23 ml) at 130° C. for 2 days following the procedure described in Example 1 (vi). The reaction mixture was acidified with aqueous hydrochloric acid and the product isolated by filtration to give the title compound as a white solid.

Provenance & Evidence