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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 442813Generated: October 29, 2026

Ethyl Acetate → HCID 70258744, compound

https://huagongshe.com/reaction/442813

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl AcetateHCID 8857—
ReactantHCID 21309177HCID 21309177—
ReactantHydrogen chloride-ethyl acetateHCID 21866389—
ProductHCID 70258744HCID 7025874482%

Reaction Steps

To a solution of N-tert.-butoxycarbonyl-4-(4-fluorophenyl)-L-phenylalanine benzyl ester (700 mg) in ethyl acetate (3.2 ml) was added 4.1N hydrogen chloride/ethyl acetate (3.8 ml). The mixture was stirred at room temperature for 17 hours. The reaction mixture was concentrated in vacuo to give 3.1 g (82%) of the titled compound (reference compound No. 1-1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05891912
Source datasetuspto-grants-1999_04
ORD IDord-1fa5672dd48b48a0a26adfff7ce1a674
Source noteuspto-grants-1999_04