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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 442877Generated: October 29, 2026

Ethyl indole-2-carboxylate → Ethyl 3-{bis[4-(methoxymethoxy)phenyl]methyl}-indole-2-carboxylate

https://huagongshe.com/reaction/442877

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl indole-2-carboxylateHCID 73125—
ReactantHCID 54082355HCID 54082355—
ProductEthyl 3-{bis[4-(methoxymethoxy)phenyl]methyl}-indole-2-carboxylateHCID 7014659789%

Reaction Steps

Substantially the same procedure as in Example 1 was repeated using 4,4'-bis(methoxymethoxy)benzhydrol (6.22 g, 32.9 mmol) and ethyl indole-2-carboxylate (10.0 g, 32.9 mmol) to give 12.9 g (yield: 89%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05891902
Source datasetuspto-grants-1999_04
ORD IDord-96fe846d8fbf4eaf9011378fe735e103
Source noteuspto-grants-1999_04