反应详情

Tetrahydro-2,5-dioxo-3-furansulfonic acid sodium salt was prepared by stirring 1.71 moles of sulfosuccinic acid with 1.87 moles of sodium hydroxide at 50° C. until a milky suspension formed and then adding 1 kg acetic anhydride over 6 hours. After cooling, 1 L of ethyl acetate was added and the mixture was filtered. The filter cake was washed with 500 mL ethyl acetate. On drying 344.32 g of white crystalline product was obtained. 13C-NMR (d6-DMSO) 171.3, 167.2, 60.4, 34.0 ppm.

1. customformed
2. temperatureAfter cooling
3. filtrationthe mixture was filtered
4. washThe filter cake was washed with 500 mL ethyl acetate
5. dry with materialOn drying 344.32 g of white crystalline product
6. customwas obtained