Hydrochloric Acid → HCID 70204754, compound

Participants

Reaction Steps

A solution of N-tert-butoxycarbonyl-4-(3-trifluoromethoxy-benzyl)-4-hydroxymethylpiperidine (2.9 g) in dichloromethane (100 mL) at 0° C. was saturated with hydrogen chloride gas. The resultant solution was sealed with a rubber septum and stirred at room temp. for 2.5 h. The product solution was concentrated under vacuum to provide the title compound.

Provenance & Evidence