Triethylamine → N-(2-Tridecyl)methanesulfonamide

HRID 443349Notes

Reaction equation

HRID 443349 reaction equation
[NH2:1][CH:2]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])[CH3:3].C(N(CC)CC)C.[CH3:22][S:23](Cl)(=[O:25])=[O:24]>C(Cl)Cl>[CH3:3][CH:2]([NH:1][S:23]([CH3:22])(=[O:25])=[O:24])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 1232972-Aminotridecane

Product 1

HCID 54273800N-(2-Tridecyl)methanesulfonamide

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of 10 g (50 mmol) 2-aminotridecane and 5 g triethylamine in 100 ml methylene chloride is added 6 g methanesulfonyl chloride while cooling and stirring for a period of 10 minutes. After one hour of additional stirring, it was allowed to stand over night. The reaction mixture was subsequently transferred to a separatory funnel, washed three times with water, dried over Na2SO4, evaporated to a white solid and dried in a vacuum oven.

Workup

  1. temperaturewhile cooling
  2. waitAfter one hour of additional stirring, it was allowed
  3. waitto stand over night
  4. customThe reaction mixture was subsequently transferred to a separatory funnel
  5. washwashed three times with water
  6. dry with materialdried over Na2SO4
  7. customevaporated to a white solid
  8. customdried in a vacuum oven

Sources & evidence

ORD record
ord-5b270a0feb0649bfaa1ec459754c3e8e
Source dataset
uspto-grants-1981_04
Patent number
US04260497

Reaction notes

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