Hydrochloric Acid → HCID 86737673, compound

Participants

Reaction Steps

A portion of Compound IV was converted to its hydrochloride salt by combining it with concentrated HCl in 10 ml of ethanol and evaporating the solvent. Toluene was added and the solution concentrated to dryness under vacuum. The residue was dissolved in a small amount of MeOH whereupon ethyl acetate was added and the solution concentrated at which point the solid was collected. This material whose structure was confirmed by mass spectral and elemental analysis was designated 179-A-19 and tested as described in Example III, infra. The other portion was left in the form of its free base and used in the experiment described in Example II.

Provenance & Evidence