HCID 15584879, compound → HCID 23467118, compound

Participants

Reaction Steps

1.0 g. (3.48 mmoles) of 9-bromo-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid is dissolved in 4 ml. of pyridine and the solution is allowed to stand for 3 days at room temperature. The precipitated crystals are filtered and washed with chloroform. 0.75 g. (66.9%) of 1-(6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-9-yl)-pyridinium bromide is obtained. Melting point: 250°-252° C. After recrystallization twice from methanol the melting point is increased to 270°-272° C.

Provenance & Evidence