Hydrochloric Acid → HCID 23467142, compound

HRID 443417Notes

Reaction equation

HRID 443417 reaction equation
C([C:9]1[C:14]([OH:15])=[CH:13][N:12]=[C:11]([CH2:16][CH:17]([NH:19][CH3:20])[CH3:18])[C:10]=1C(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1.[ClH:29]>>[ClH:29].[ClH:29].[CH3:20][NH:19][CH:17]([CH3:18])[CH2:16][C:11]1[CH:10]=[CH:9][C:14]([OH:15])=[CH:13][N:12]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 23467139HCID 23467139, compound

Product 1

HCID 23467142HCID 23467142, compound

Procedure

The solution of 0.15 g of dibenzoyl-2-(2-methylaminopropyl)-5-pyridinol in 5 ml of 5 N hydrochloric acid is refluxed for 23 hours, cooled, twice washed with 5 ml of diethyl ether and evaporated, to yield the 2-(2-methylaminopropyl)-5-pyridinol dihydrochloride, showing in the mass-spectrum peaks at 165, 151, 109 and 58 m/e.

Workup

  1. temperaturecooled
  2. washtwice washed with 5 ml of diethyl ether
  3. customevaporated

Sources & evidence

ORD record
ord-ab16db373b8f4ad5819cc08022b6264d
Source dataset
uspto-grants-1981_04
Patent number
US04260619

Reaction notes

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