Hydrochloric Acid → 76906-72-4

HRID 443419Notes

Reaction equation

HRID 443419 reaction equation
C([C:9]1[C:14]([OH:15])=[CH:13][N:12]=[C:11]([CH2:16][CH:17]([NH:19][CH:20]([CH3:22])[CH3:21])[CH3:18])[C:10]=1C(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1.[ClH:31]>>[ClH:31].[ClH:31].[CH:20]([NH:19][CH:17]([CH3:18])[CH2:16][C:11]1[CH:10]=[CH:9][C:14]([OH:15])=[CH:13][N:12]=1)([CH3:22])[CH3:21]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 23467153HCID 23467153, compound

Product 1

HCID 2013828176906-72-4

Procedure

Similarly, the mixture of 0.1 g of dibenzoyl-2-(2-isopropylaminopropyl)-5-pyridinol and 10 ml of 5 N hydrochloric acid may be refluxed for three days, cooled, filtered, evaporated and the residue triturated with acetone, to yield the 2-(2-isopropylaminopropyl)-5-pyridinol dihydrochloride melting at 199°-204°; it is identical with that obtained according to Examples 1, 3 and 8.

Workup

  1. temperaturemay be refluxed for three days
  2. temperaturecooled
  3. filtrationfiltered
  4. customevaporated
  5. customthe residue triturated with acetone

Sources & evidence

ORD record
ord-8f1d4ecba30d442289c8d990dad58f88
Source dataset
uspto-grants-1981_04
Patent number
US04260619

Reaction notes

Loading…