Hydrochloric Acid → HCID 23467142, compound

HRID 443420Notes

Reaction equation

HRID 443420 reaction equation
[C:1]([N:11](C)[CH:12]([CH3:21])[CH2:13][C:14]1[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][N:15]=1)(OCC1C=CC=CC=1)=O.[ClH:23]>>[ClH:23].[ClH:23].[CH3:1][NH:11][CH:12]([CH3:21])[CH2:13][C:14]1[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][N:15]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 23467141HCID 23467141, compound

Product 1

HCID 23467142HCID 23467142, compound

Procedure

The mixture of 0.08 g of 2-(N-carbobenzyloxy-2-methylaminopropyl)-5-pyridinol and 2.5 ml of 5 N hydrochloric acid is refluxed for 23 hours, cooled and extracted with diethyl ether. The extract is dryed and evaporated, to yield the 2-(2-methylaminopropyl)-5-pyridinol dihydrochloride, which is identical with that obtained according to Example 15.

Workup

  1. temperatureis refluxed for 23 hours
  2. temperaturecooled
  3. extractionextracted with diethyl ether
  4. customevaporated

Sources & evidence

ORD record
ord-a4fc549990474419a0083efbedfec7f1
Source dataset
uspto-grants-1981_04
Patent number
US04260619

Reaction notes

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