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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 443466Generated: October 31, 2026

Chlorosuccinimide → L-Valine, N-[2-chloro-4-(trifluoromethyl)phenyl]-

https://huagongshe.com/reaction/443466

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorosuccinimideHCID 31398—
ReactantValine, N-[4-(trifluoromethyl)phenyl]-HCID 13388454—
SolventCarbon TetrachlorideHCID 5943—
ProductL-Valine, N-[2-chloro-4-(trifluoromethyl)phenyl]-HCID 156536—

Reaction Steps

Following the method of Example 6, (S)-2-(4-trifluoromethylphenylamino)-3-methylbutanoic acid and N-chlorosuccinimide in carbon tetrachloride are reacted, yielding (S)-2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04260633
Source datasetuspto-grants-1981_04
ORD IDord-538744adec3f416388c8076db8a981d7
Source noteuspto-grants-1981_04