Hydrochloric Acid → N-(Cyclohexyl)-N-(2-chloroethyl)-aminomethylphosphonic Acid

HRID 443482Notes

Reaction equation

HRID 443482 reaction equation
Cl.[Cl:2][CH2:3][CH2:4][NH:5][CH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1.[P:12]([OH:15])([OH:14])[OH:13].Cl.[CH2:17]=O>O>[CH:6]1([N:5]([CH2:17][P:12](=[O:15])([OH:14])[OH:13])[CH2:4][CH2:3][Cl:2])[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 712FormaldehydeHCID 107909Phosphorous acidHCID 13756691N-(2-chloroethyl)cyclohexanamine hydrochloride

Product 1

HCID 20564015N-(Cyclohexyl)-N-(2-chloroethyl)-aminomethylphosphonic Acid

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A total of 101 parts of N-(2-chloroethyl)cyclohexylamine hydrochloride, 41.5 parts phosphorous acid in 101 parts water, 75 parts of 37% aqueous hydrochloric acid, and 104 parts of 37% aqueous formaldehyde were used to prepare Reagent E-2.

Workup

  1. customto prepare Reagent E-2

Sources & evidence

ORD record
ord-5503561e427b4a0b8da80875d0cc19c6
Source dataset
uspto-grants-1981_04
Patent number
US04260738

Reaction notes

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