Potassium Hydroxide → HCID 23468292, compound

Participants

Reaction Steps

A solution of 4.3 g. of ethyl 4-[N-trifluoroacetyl-2-(4-cyano-1-naphthyloxy)ethylamino]benzoate and 4.3 g. of potassium hydroxide in 100 ml. of 95% ethanol is refluxed for 3 hours. After cooling, diluting with 100 ml. of water and acidification to pH 4 with concentrated hydrochloric acid, the white solid is collected, washed with water and dried, m.p. 254°-256° C.

Provenance & Evidence