Sodium Hydroxide → HCID 178434071, compound

HRID 443694Notes

Reaction equation

HRID 443694 reaction equation
[CH3:1][N:2]1[C:6]([OH:7])=[C:5]([C:8](=[O:17])[C:9]2[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][C:10]=2[Cl:16])[C:4]([CH3:18])=[N:3]1.[OH-].[Na+].[Cl-].[Ca+2:22].[Cl-]>O>[Ca:22].[CH3:1][N:2]1[C:6]([OH:7])=[C:5]([C:8](=[O:17])[C:9]2[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][C:10]=2[Cl:16])[C:4]([CH3:18])=[N:3]1

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 5284359Calcium ChlorideHCID 178434070HCID 178434070, compound

Product 1

HCID 178434071HCID 178434071, compoundYield 79%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

In 50 ml. of water is suspended 2.85 g. of 1,3-dimethyl-4-(2,4-dichlorobenzoyl)-5-hydroxypyrazole and the suspension is dissolved in about 5 ml. of a 2 N aqueous solution of sodium hydroxide. A solution of 1.11 g. of calcium chloride in 10 ml. of water is added and the resulting mixture is stirred. The so separated precipitates are recovered by filtration and dried to give 2.4 g. of the desired product as white powder melting at about 260° C. Yield 79.0%.

Workup

  1. customThe so separated
  2. customprecipitates
  3. filtrationare recovered by filtration
  4. customdried
  5. customto give 2.4 g

Sources & evidence

ORD record
ord-83dec728757e4e9ba6e0095a8904d06f
Source dataset
uspto-grants-1981_04
Patent number
US04261729

Reaction notes

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