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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 44371Generated: October 29, 2026

Dimethylamine → 2-Chloro-N,N-dimethylquinazolin-4-amine

https://huagongshe.com/reaction/44371

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant2,4-DichloroquinazolineHCID 252886—
Product2-Chloro-N,N-dimethylquinazolin-4-amineHCID 12684342—

Reaction Steps

Prepared as in Example 38 from 2,4-dichloroquinazoline and dimethylamine. 1H NMR (400 MHz, CDCl3) δ3.42 (s, 6H), 7.42-7.39 (m, 1H), 7.72-7.70 (m, 1H), 7.79-7.77 (m, 1H), 8.03-8.01 (m, 1H). MS 208 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08541421B2
Source datasetuspto-grants-2013_09
ORD IDord-48760e7dcf094b8ea1571d069c9b4819
Source noteuspto-grants-2013_09