2,2,2-Trifluoroethanol → HCID 57181364, compound

Participants

Reaction Steps

A solution of 2.50 g (0.00856 mol) of 3-(α,α,α-trifluoro-m-tolyl)-4-isothiazolecarbonyl chloride and 50 ml of 2,2,2-trifluoroethanol was held at reflux for 40 minutes, was allowed to stand overnight, and was concentrated under vacuum (to 90° at 0.1 torr) to give 2.68 g (88%) of oil, nD24 =1.4976.

Provenance & Evidence