Hydrazine → 5-Methylthio-2-aminobenzoic acid hydrazide

HRID 443833Notes

Reaction equation

HRID 443833 reaction equation
[CH3:1][S:2][C:3]1[CH:4]=[CH:5][C:6]2[NH:11]C(=O)[O:9][C:8](=O)[C:7]=2[CH:14]=1.[NH2:15][NH2:16]>O>[CH3:1][S:2][C:3]1[CH:4]=[CH:5][C:6]([NH2:11])=[C:7]([CH:14]=1)[C:8]([NH:15][NH2:16])=[O:9]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 127132556-methylsulfanyl-1H-benzo[d][1,3]oxazine-2,4-dione

Product 1

HCID 127132375-Methylthio-2-aminobenzoic acid hydrazide

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

6-methylthio-2H-3,1-benzoxazine-2,4-(1H)-dione (25.11 g; 0.72 mole) is added to a cold solution of 54.4% hydrazine (75 ml) in water (75 ml). After stirring at room temperature overnight, the while solid is filtered, washed with cold water and dried. Yield 21.3 g; mp 124°-127°.

Workup

  1. filtrationthe while solid is filtered
  2. washwashed with cold water
  3. customdried

Sources & evidence

ORD record
ord-f2b76511e3944de0b55d8c5008551fd3
Source dataset
uspto-grants-1981_04
Patent number
US04261996

Reaction notes

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