HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 12552502, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 178524062 | HCID 178524062 | — |
| Product | HCID 12552502 | HCID 12552502 | 86% |
Reaction Steps
A mixture of 2.29 g of 4,9-dihydro-9-oxo-pyrazolo-[5,1-b]quinazoline-2-carboxylic acid, 5.52 g of anhydrous potassium carbonate and 34.2 g of methyl iodide in 100 ml of dimethyl formamide is stirred at room temperature for 3 days. Water is added and the white solid is filtered off to give 2.2 g (86%) of the ester; mp 287°-289° C. (d).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04261997 |
| Source dataset | uspto-grants-1981_04 |
| ORD ID | ord-b0c74c0a3fbe4071b2c511c5e53ee02a |
| Source note | uspto-grants-1981_04 |