HCID 23466055, compound → HCID 12878322, compound

HRID 443953Notes

Reaction equation

HRID 443953 reaction equation
[OH:1][C:2]1([CH3:27])[CH2:8][CH:7]([CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][C:14]([O:17]CC3C=CC=CC=3)=[C:13]([O:25][CH3:26])[CH:12]=2)[O:6][C:4](=[O:5])[CH2:3]1>[Pd].C(OCC)(=O)C>[OH:1][C:2]1([CH3:27])[CH2:8][CH:7]([CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][C:14]([OH:17])=[C:13]([O:25][CH3:26])[CH:12]=2)[O:6][C:4](=[O:5])[CH2:3]1

Participants

4

Reactant 1

HCID 23466055HCID 23466055, compound

Product 1

HCID 12878322HCID 12878322, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

Using 140 mg of 3-hydroxy-3-methyl-7-(p-benzyloxy-m-methoxyphenyl)-5-heptanolide, 140 mg of 5% palladium-charcoal and 14 ml of ethyl acetate, the reaction and the purification of the product were carried out according to the method described in Example 27 affording 75 mg of the desired compound melting at 162°-164° C.

Workup

  1. customthe reaction
  2. customthe purification of the product

Sources & evidence

ORD record
ord-64f5f691bd99483cafa4f49e13890c39
Source dataset
uspto-grants-1981_04
Patent number
US04262013

Reaction notes

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