Sodium Methoxide → HCID 44119864, compound

HRID 443973Notes

Reaction equation

HRID 443973 reaction equation
[Cl:1][C@H:2]1[C@@H:9]([OH:10])[C@H:8]([OH:11])[C@@H:7]([CH2:12][OH:13])[O:6][C@@H:3]1[O:4]C.C[O-].[Na+]>CO>[Cl:1][C@@H:2]([C@H:9]([C@@H:8]([C@@H:7]([CH2:12][OH:13])[OH:6])[OH:11])[OH:10])[CH:3]=[O:4]

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 54296360HCID 54296360, compound

Product 1

HCID 44119864HCID 44119864, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The methyl 2-chloro-2-deoxy-mannopyranoside (6) was dissolved in the minimum of methanol and the pH adjusted to 10 by addition of 1 molar sodium methoxide. The solution was kept for 2-5 hours at room temperature and evaported to give the 2-chloro-2-deoxy mannose in about 90% yield.

Sources & evidence

ORD record
ord-53771700ae9b47ed8dbb73e062ca1114
Source dataset
uspto-grants-1981_04
Patent number
US04262115

Reaction notes

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