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HRID444073

反应详情

EQUATION

反应方程式

HRID 444073 的结构方程式

REACTANTS

反应物

2
结构：CN(C)C=O
HCID6228

N,N-Dimethylformamide

C3H7NO

结构：CC1(C)C(=O)Oc2ccc(Br)cc21
HCID16220634

未命名化合物

PRODUCTS

生成物

1
结构：CC1(C)C(=O)Oc2ccc(C#N)cc21
HCID20536247

未命名化合物

收率 45%

PROCEDURE

实验过程

5-Bromo-2,3-dihydro-3,3-dimethylbenzofuran-2-one (39.2 g, 0.162 mole) was treated with cuprous cyanide (17.9 g, 0.2 mole) in dimethyl formamide (40 ml) (as in example 2). Recrystallisation (twice) of the product from ethanol yielded 14 g (45%) title product m.p. 138°-140° C.

WORKUP

后处理

  1. customRecrystallisation (twice) of the product from ethanol