反应详情

The product of Example 45 (2 g) was boiled under reflux in water (5 ml) and acetone (15 ml) for 31/2 hours. The product was then extracted into diethyl ether, the extracted solution then being washed twice with water, dried over sodium sulphate and run down under vacuum to give 1.7 g of crude product. Recrystallisation from toluene gave pure title product (1.3 g), mp 127°-129° C.

1. custom2 hours
2. extractionThe product was then extracted into diethyl ether
3. washthe extracted solution then being washed twice with water
4. dry with materialdried over sodium sulphate
5. customto give 1.7 g of crude product
6. customRecrystallisation from toluene