HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 13013932, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Methyl 10,11-dihydrodibenzo[b,f][1,4]thiazepin-3-carboxylate 5,5-Dioxide | HCID 13013933 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 13013932 | HCID 13013932 | — |
Reaction Steps
Stir a mixture of 3.03 gm. (10 mmole) of the ester of Example 15, 2.24 gm. (20 mmole) of 85% aqueous potassium hydroxide, 11 ml. of water, 55 ml. of ethanol and 5.5 ml. of dioxane under nitrogen for 2 hours. Concentrate the reaction mixture to the point of crystallization and dilute with 40 ml. of water. Filter and acidify with acetic acid. Separate the precipitate by filtration and wash with water and dry to obtain the title product (m.p. 304°-306° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04263207 |
| Source dataset | uspto-grants-1981_04 |
| ORD ID | ord-20952a204f2a4749b2c12d833414a7ee |
| Source note | uspto-grants-1981_04 |