Benzene → HCID 23464491, compound

HRID 444166Notes

Reaction equation

HRID 444166 reaction equation
O[CH2:2][C:3]1[CH:18]=[CH:17][C:6]2[C:7](=[O:16])[NH:8][C:9]3[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=3[S:11][C:5]=2[CH:4]=1.C1C=CC=CC=1.P(Br)(Br)[Br:26].O>C1(C)C=CC=CC=1>[Br:26][CH2:2][C:3]1[CH:18]=[CH:17][C:6]2[C:7](=[O:16])[NH:8][C:9]3[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=3[S:11][C:5]=2[CH:4]=1

Participants

6

Reactant 4

HCID 241BenzeneHCID 962WaterHCID 24614Phosphorus tribromideHCID 23464485HCID 23464485, compound

Product 1

HCID 23464491HCID 23464491, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Dissolve 4.43 gm. of the alcohol of Step A in 100 cc. of benzene and add 1 cc (10.5 mmole) of phosphorous tribromide. Stir at room temperature for 1 hour, add water and then dilute with toluene. Wash three times with water, dry and strip to a solid residue.

Workup

  1. dissolutionDissolve 4.43 gm
  2. washWash three times with water
  3. customdry

Sources & evidence

ORD record
ord-6b4c7ac2cd9d459686713386e7887db3
Source dataset
uspto-grants-1981_04
Patent number
US04263207

Reaction notes

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