Bromoethene → HCID 13133043, compound

HRID 444208Notes

Reaction equation

HRID 444208 reaction equation
[CH3:1][N:2]1[C:10]2[NH:11][C:12](=[O:19])[C:13]3[C:18]([C:9]=2[C:8]2[CH:7]=[C:6]([Cl:20])[CH:5]=[CH:4][C:3]1=2)=[CH:17][CH:16]=[CH:15][CH:14]=3.[H-].[Na+].[CH:23](Br)=[CH2:24]>>[CH:23]([O:19][C:12]1[C:13]2[C:18](=[CH:17][CH:16]=[CH:15][CH:14]=2)[C:9]2[C:8]3[CH:7]=[C:6]([Cl:20])[CH:5]=[CH:4][C:3]=3[N:2]([CH3:1])[C:10]=2[N:11]=1)=[CH2:24]

Participants

4

Reactant 3

HCID 11641BromoetheneHCID 24758Sodium hydrideHCID 13133047HCID 13133047, compound

Product 1

HCID 13133043HCID 13133043, compound

Procedure

5-Vinyloxy-7-methyl-10-chloro-7H-indolo(2,3-c)isoquinoline (melting point 121°-124° C.) is prepared from 7-methyl-10-chloro-7H-indolo(2,3-c)isoquinolin-5(6H)-one, sodium hydride and vinyl bromide by the method described in Example 8.

Sources & evidence

ORD record
ord-b463216c3b2447ffa30b9228cf167a9b
Source dataset
uspto-grants-1981_04
Patent number
US04263304

Reaction notes

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