Epichlorohydrin → HCID 13408410, compound

HRID 444217Notes

Reaction equation

HRID 444217 reaction equation
[CH2:1]([C:4]1[C:5]([OH:23])=[CH:6][CH:7]=[C:8]2[C:13]=1[O:12][C:11](=[O:14])[CH:10]=[C:9]2[O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[CH:2]=[CH2:3].[CH2:24]([CH:26]1[O:28][CH2:27]1)Cl>C(O)C>[CH2:1]([C:4]1[C:5]([O:23][CH2:24][CH:26]2[O:28][CH2:27]2)=[CH:6][CH:7]=[C:8]2[C:13]=1[O:12][C:11](=[O:14])[CH:10]=[C:9]2[O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[CH:2]=[CH2:3]

Participants

4

Reactant 2

HCID 7835EpichlorohydrinHCID 13408409HCID 13408409, compound

Product 1

HCID 13408410HCID 13408410, compoundYield 82%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Reaction of 8-allyl-4-benzyloxy-7-hydroxycoumarin (12.33 g; 0.04 mole) with epichlorhydrin (25 ml) as described in Example 2(a) gave 11.97 g (82%) of product of m.p. (ethanol) 118°-121° C., νmax (mull) 1715, 1618, 1565 cm-1 (Found; C, 72.45; H, 5.53; C22H20O5 requires; C, 72.51; H, 5.53%).

Sources & evidence

ORD record
ord-f5a0cc7fa50b408387232dac9c6765b5
Source dataset
uspto-grants-1981_04
Patent number
US04263299

Reaction notes

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