Methane → HCID 54710798, compound

Participants

Reaction Steps

Hydrogenation of a solution of 1-[3-(8-allyl-4-benzyloxycoumarin-7-yloxy)-2-hydroxypropyl]-4-(4-chlorobenzyl)piperazine (7.2 g) in DMF (200 ml) over 10% palladinized charcoal at atmospheric pressure until two equivalents of hydrogen were absorbed gave 4.85 g (80%) of material of m.p. (aqueous ethanol) 107° C. (Found; C, 63.90; H, 6.59; N, 5.20; Cl, 6.53; C26H31N2O5Cl requires; C, 64.12; H, 6.42; N, 5.75; Cl, 7.28%).

Provenance & Evidence