反应详情

N-Bromosuccinimide (9.59 g; 0.054 mole) was added to stirred solution of 4-ethoxy-7-methylcoumarin (11 g; 0.054 mole) in carbontetrachloride (600 ml) followed by a catalytic quantity of azo bisbutyronitrile. After refluxing the mixture for 1 hr the solvent was removed in vacuo and the residue recrystallized from ethanol to give 11.73 g (77%) of product of m.p. 150°-3° C. Further recrystallization gave material of m.p. 152°-155° C.

1. temperatureAfter refluxing the mixture for 1 hr the solvent
2. customwas removed in vacuo
3. customthe residue recrystallized from ethanol