反应详情

60 g of 2-formamidotridecane are refluxed in 400 ml of 2 N HCl for 6 hours. The reaction mixture is then cooled in an ice bath, made alkaline with conc. NaOH, extracted with ether, and the ethereal extract is dried over Na2SO4. The ether is distilled off and the residue is then distilled in vacuo, affording 40 g of 2-aminotridecane. Boiling point: 68°-71° C./0.05.

1. temperatureThe reaction mixture is then cooled in an ice bath
2. extractionextracted with ether
3. extractionthe ethereal extract
4. dry with materialis dried over Na2SO4
5. distillationThe ether is distilled off
6. distillationthe residue is then distilled in vacuo