HRID444256

反应详情

EQUATION

反应方程式

REACTANTS

反应物

反应SMILES：NC1C(=O)N2C(C(=O)O)=C(CSc3nncs3)CS[C@H]12

HCID12889187

未命名化合物

HCID54347340

未命名化合物

PRODUCTS

产物

反应SMILES：CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nncs3)CS[C@H]12)c1csnn1

HCID131712185

未命名化合物

收率 43.7%

PROCEDURE

实验过程

2-Methoxyimino-2-(1,2,3-thiadiazol-4-yl)-acetic acid (syn isomer) (0.6 g.) and 7-amino-3-(1,3,4-thiadiazol-2-yl)thiomethyl-3-cephem-4-carboxylic acid (1.1 g.) were reacted according to similar manners to those of Examples 12 and 15 to give 7-[2-methoxyimino-2-(1,2,3-thiadiazol-4-yl)acetamido]-3-(1,3,4-thiadiazol-2-yl)thiomethyl-3-cephem-4-carboxylic acid (syn isomer) (0.7 g.), mp 90° to 98° C. (dec.).