HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Amino-3-(1,3,4-thiadiazol-2-ylthiomethyl)-3cephem-4-carboxylic acid → HCID 131712185, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Amino-3-(1,3,4-thiadiazol-2-ylthiomethyl)-3cephem-4-carboxylic acid | HCID 12889187 | — |
| Reactant | 2-Methoxyimino-2-(1,2,3-thiadiazol-4-yl)acetic acid | HCID 54347340 | — |
| Product | HCID 131712185 | HCID 131712185 | 43.7% |
Reaction Steps
2-Methoxyimino-2-(1,2,3-thiadiazol-4-yl)-acetic acid (syn isomer) (0.6 g.) and 7-amino-3-(1,3,4-thiadiazol-2-yl)thiomethyl-3-cephem-4-carboxylic acid (1.1 g.) were reacted according to similar manners to those of Examples 12 and 15 to give 7-[2-methoxyimino-2-(1,2,3-thiadiazol-4-yl)acetamido]-3-(1,3,4-thiadiazol-2-yl)thiomethyl-3-cephem-4-carboxylic acid (syn isomer) (0.7 g.), mp 90° to 98° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04263291 |
| Source dataset | uspto-grants-1981_04 |
| ORD ID | ord-384003df78734693a9042fe957cc0ef9 |
| Source note | uspto-grants-1981_04 |