1-Hexanol → HCID 178527824, compound

HRID 444295Notes

Reaction equation

HRID 444295 reaction equation
C(O)CCCCC.[CH2:8]1[O:12][C:11]2[CH:13]=[C:14]([CH:17](O)[C:18]([C:20]3[CH:25]=[CH:24][C:23]4[O:26][CH2:27][O:28][C:22]=4[CH:21]=3)=O)[CH:15]=[CH:16][C:10]=2[O:9]1.[NH2:30][C:31]([NH2:33])=[S:32]>O>[CH2:8]1[O:9][C:10]2[CH:16]=[CH:15][C:14]([C:17]3[N:30]=[C:31]([SH:32])[NH:33][C:18]=3[C:20]3[CH:25]=[CH:24][C:23]4[O:26][CH2:27][O:28][C:22]=4[CH:21]=3)=[CH:13][C:11]=2[O:12]1

Participants

5

Reactant 3

HCID 81031-HexanolHCID 977861,2-Bis(1,3-benzodioxol-5-yl)-2-hydroxyethanoneHCID 2723790Thiourea

Product 1

HCID 178527824HCID 178527824, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
0 °C

Procedure

A hexanol solution (170 ml.) of 10.9 g. (0.036 mole) of piperoin and 5.5 g. (0.072 mole) of thiourea was refluxed for 4 hours, with continuous azeotropic water removal. The mixture was cooled to 0° C. and the solid collected, washed with ether and dried. Recrystallization from dimethylformamide gave 4,5-bis(3,4-methylenedioxyphenyl)-2-mercaptoimidazole, m.p. 282°-283° C.

Workup

  1. customthe solid collected
  2. washwashed with ether
  3. customdried
  4. customRecrystallization from dimethylformamide

Sources & evidence

ORD record
ord-371c66208734447290b160f69a24e111
Source dataset
uspto-grants-1981_04
Patent number
US04263311

Reaction notes

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