HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Piperidin-4-yl)imidazolidin-2-one → HCID 23463820, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Piperidin-4-yl)imidazolidin-2-one | HCID 13031757 | — |
| Reactant | 2-Benzyloxy-3-(2,3-epoxypropoxy)-pyridine | HCID 23463815 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 23463820 | HCID 23463820 | — |
Reaction Steps
4.8 g of 2-benzyloxy-3-(2,3-epoxypropoxy)-pyridine and 3.0 g of 1-(4-piperidyl)-imidazolidin-2-one are dissolved in 50 ml of isopropanol and the solution is stirred for 15-18 hours at 20-30°. The crystals which have precipitated out are filtered off with suction and washed with ether and yield 1-{1-[2-hydroxy-3-(2-benzyloxy-3-pyridyloxy)-propyl]-4-piperidyl}-imidazolidin-2-one with a melting point of 145°-147°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04264599 |
| Source dataset | uspto-grants-1981_04 |
| ORD ID | ord-305f614cadc94191a628ec743c5b8a9b |
| Source note | uspto-grants-1981_04 |