Hydrochloric Acid → 1-(2,6-Dichlorobenzoyl)-3-(6-(4-chlorophenylthio)-3-pyridinyl)urea, hydrochloride salt

HRID 444469Notes

Reaction equation

HRID 444469 reaction equation
[Cl:1][C:2]1[CH:27]=[CH:26][CH:25]=[C:24]([Cl:28])[C:3]=1[C:4]([NH:6][C:7]([NH:9][C:10]1[CH:11]=[N:12][C:13]([S:16][C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][CH:18]=2)=[CH:14][CH:15]=1)=[O:8])=[O:5].Cl>>[ClH:1].[Cl:28][C:24]1[CH:25]=[CH:26][CH:27]=[C:2]([Cl:1])[C:3]=1[C:4]([NH:6][C:7]([NH:9][C:10]1[CH:11]=[N:12][C:13]([S:16][C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][CH:18]=2)=[CH:14][CH:15]=1)=[O:8])=[O:5]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 12912740HCID 12912740, compound

Product 1

HCID 1317121961-(2,6-Dichlorobenzoyl)-3-(6-(4-chlorophenylthio)-3-pyridinyl)urea, hydrochloride salt

Procedure

1-(2,6-Dichlorobenzoyl)-3-(6-(4-chlorophenylthio)-3-pyridinyl)urea (2.0 grams) was refluxed in 100 ml. of concentrated HCl (37%) for 4 hours. The reaction mixture was cooled and the product separated by filtration, yield 1.5 grams, m.p., 214°-217° C.

Workup

  1. temperatureThe reaction mixture was cooled
  2. customthe product separated by filtration, yield 1.5 grams, m.p., 214°-217° C.

Sources & evidence

ORD record
ord-f840c91376c24a519f9115c0519d4b2a
Source dataset
uspto-grants-1981_04
Patent number
US04264605

Reaction notes

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