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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 444708Generated: October 30, 2026

HCID 67223761, compound → HCID 67224193, compound

https://huagongshe.com/reaction/444708

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67223761HCID 67223761—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 67224193HCID 67224193100.2%

Reaction Steps

A solution of 3-Benzyl-imidazolidine-1,5-dicarboxylic acid 1-tert-butyl ester 5-methyl ester (1.0 g, 3.12 mmol) in MeOH (20 mL) was added Pd/C (0.20 g) and stirred at room temperature under H2 for two hours. The reaction mixture was filtered through celite. The filtrate was concentrated to afford Imidazolidine-1,5-dicarboxylic acid 1-tert-butyl ester 5-methyl ester (0.72 g, xx % yield) which was used for the next step directly.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08476225B2
Source datasetuspto-grants-2013_07
ORD IDord-91f298f9d8e04317b7209863e592c337
Source noteuspto-grants-2013_07