1-Bromo-2-fluorobenzene → HCID 86678555, compound

Participants

Reaction Steps

Intermediate XXIX-1 was obtained following general procedure L: Starting from rac-(3aR,6aR)-3-difluoromethyl-5,5-difluoro-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]isoxazole, the reaction with 1-bromo-2-fluoro-benzene yielded the product rac-(3S,3aR,6aR)-3-difluoromethyl-5,5-difluoro-3-(2-fluoro-phenyl)-hexahydro-cyclopenta[d]isoxazole as a light brown oil. MS: m/z=294.4 [M+H]+.

Provenance & Evidence